Adel El-Badrawy
Faculty of Medicine and Oncology Center- Mansoura University, Egypt
Posters-Accepted Abstracts: J Cancer Sci Ther
Purpose: To review the multidetector CT findings of seven cases with spontaneous regression of hepatocellular carcinomas (HCC). Materials and methods: This retrospective study included 7 patients confirmed with diagnosis of HCC. Triphasic CT scan using multidetector CT scanner was done for all patients. They were 2 women and 5 men. 1st patient with presented with metastatic HCC underwent fine needle aspiration cytology (FNAC) from vertebral metastasis. 2nd patient underwent only one session of transarterial chemo-embolization. 3rd patient exposed to blunt trauma to chest wall with rib fissure fracture. 4th patient presented with two HCCs underwent radio-frequency ablation of one lesion. 5th patient underwent FNAC from HCC and exposed to fracture neck femur. No interventional technique done in 6th patient. 7th patient underwent FNAC from hepatic focal lesion. Results: Complete regression of primary HCC and metastases occurred in 1st patient. 2nd patient showed partial lipidol uptakes of HCC with complete regression of HCC on follow up. Incomplete regression of HCC detected in 3rd, 6th and 7th patients. Partial regression of non-ablated lesion detected in the 4th patient. Complete regression of HCC occurred on 5th patient. Conclusion: Spontaneous regression of HCC is an interesting phenomenon. It has been hypothesized that invasive techniques may be linked. Invasive techniques may initiate immunologic mechanisms that may be involved in the regression. Clinical application: More reports and accumulation of such cases should help to clarify the mechanisms, contribute to a further understanding of this phenomenon and may lead to a new treatment strategy for HCC.
Email: adelelbadrawy@hotmail.com
Cancer Science & Therapy received 3968 citations as per Google Scholar report
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