Enteral glutamine supplementation in surgical patients with head and neck malignancy: A randomized controlled trial

9^th Indo Global Summit on Cancer Therapy

November 02-04, 2015 Hyderabad, India

Mawaddah Azman, Mohd Razif Mohd. Yunus, Suhaina Sulaiman and Syed Nabil Syed Omar

Universiti Kebangsaan Malaysia, Malaysia

Posters-Accepted Abstracts: J Cancer Sci Ther

Abstract :

Background: Glutamine supplementation is a novel approach to perioperative nutritional management. Methods: This study was a prospective randomized clinical trial of effects of enteral glutamine supplementation in surgical patients with head and neck malignancy in a tertiary center. This study measured the effects of supplementation within 4 weeks of the postoncologic surgical period in relation to fat-free mass, serum albumin, and quality of life scores. Results: The study population consisted of 44 patients. There was significant difference in serum albumin (p<0.001), fat-free mass (p<0.001) and quality of life scores (p<0.05) between control and interventional groups. Significant correlation exists between fat-free mass and quality of life score difference in our study population (p<0.05). Conclusion: Enteral glutamine supplementation significantly improves fat-free mass, serum albumin and quality of life scores postoperatively and maintenance of lean body mass correlated with improved postoperative outcomes in terms of the patient�s quality of life.

Biography :

Email: mawaddah1504@yahoo.com