EFFECT OF MODERATELY CONTROLLED AEROBIC EXERCISE AND LIFESTYLE CHANGES WITH COGNITIVE BEHAVIORAL PSYCHOTHERAPY ON THE EXPRESSION OF ATHEROGENESIS-RELATED GENES IN CHILDREN WITH OVERWEIGHT AND OBESITY

2^nd International Conference on Metabolic Syndrome

August 10-11, 2017 | London, UK

Gabriela Yanet Cortes Moreno

National Polytechnic Institute, Mexico

Posters & Accepted Abstracts: J Metabolic Synd

Abstract :

The obesity epidemic in our country stems from concern and interest to fight this disease since childhood, considering markers that are potentially predictive of cardiovascular complications present at later ages. Interventions such as aerobic exercise controls and cognitive behavioural therapy are the mainstay of treatment for this condition, agreements to current paediatric clinical guidelines changes that lead these interventions at the molecular level in the expression of genes involved in endothelial dysfunction as are PRMT1, DDAH1 are now the starting point. Objective: This study evaluated the effect of moderate aerobic exercise (MAE) and controlled behaviour modification with cognitivebehavioural psychotherapy (CBP) on anthropometric, biochemical and gene expression associated with atherogenesis in children aged 6-12 years are overweight and obesity exogenous variables. Methods: 26 patients with overweight and obesity diagnosed according to the CDC tables 6-12 years, of which the peripheral blood was obtained obesity were recruited. A CBP intervention group (n = 13), and a group MAE + CBM intervention (13), both groups were treated for 12 weeks. Anthropometric and biochemical parameters were measured; gene expression was quantified by PCR in real time.