Roya Dolatkhah, Mohammad Hossein Somi, Saeed Dastgiri, Mohammad Asghari Jafarabadi and Behrooz Alizadeh
Tabriz University of Medical Sciences, Iran
Posters & Accepted Abstracts: J Cancer Sci Ther
Background and Aim: Although the early diagnosis of colorectal cancer reduces the associated death burden, administration of
screening programs is not a common practice even in developed countries. Previous studies showed the lack of national screening
programs for CRC in Iran with little information available on the screening strategies for cancer, in general. The main aim of our study
is to develop and validate a simple, practical and efficient tool to improve CRC risk assessment by identifying the high and moderate
risk of the disease.
Material and Methods: We used the NCCN (National Comprehensive Cancer Network) guidelines, because of full details about
colorectal cancer risk assessments. The original risk assessment tool was translated from English into Persian. The back-translation
method was performed, as the preferred method to measure. For the content validity, we performed a scientific panel of judges,
comprised 5 medical oncologists, 3 gastroenterologists, and 2 epidemiologists. The proportion of experts who were in agreement
with item relevance calculated as a quantitative measure of content validity, the CVI. The questionnaires were collected and content
validity ratio (CVR) was calculated for each item. The questionnaire was assessed for face validity by 15 individuals to assess its
acceptable and understandable for them.
Results: The experts evaluated every item and rated them for understandability, distinctiveness, appropriateness to the domain
of content, and relatedness to Iranian population. Based on expertsâ?? opinion about necessity and completeness of each item, the
acceptable CVR was between 1 and 0.40. Afterward, CVI was calculated to be 1 to 0.70. Moreover, the means of CVR and CVI were
0.62 and 0.93 respectively for whole the questionnaire items. Changes were made according to expertsâ?? recommendations, and final
revised questionnaire assessed for face validity. Based on participantsâ?? comments, a few items needed to some modifications and
expansion.
Discussion: The development of an executive plan to identify the most appropriate screening method and the best age group for
screening and a specific risk assessment tool is the main priority in Iran.
Keywords: Colorectal Cancer; Risk Assessment; Validity
E-mail: royadolatkhah@yahoo.com
Cancer Science & Therapy received 3968 citations as per Google Scholar report
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