Biological monitoring of occupational exposure for b-mnserum samples from iron casting workers

Global Congress on Tissue Engineering, Regenerative & Precision Medicine

December 1-2, 2016 | San Antonio, USA

Seyedtaghi Mirmohammadi

Mazandaran University of Medical Sciences, Iran

Posters & Accepted Abstracts: J Tissue Sci Eng

Abstract :

The furnace-men and melting department workers are potentially exposed to manganese particles or fume in the workplace which accumulates in their central nervous system and neurological disorder observed for exposed workers. The objective of the research was to investigate the sources and levels of manganese exposure in the foundry by correlation of bloodmanganese (B-Mn) and air-manganese (air-Mn) measurement. Air-Mn and B-Mn were measured involving workers (case= 35, control=35) who worked in a big size foundry during one year. The standard method of OSHA- ID121 was used for the air and blood assessment and atomic absorption spectroscopy (AAS) was carried out in air and blood sample analysis. The air sampling results revealed that there is a high exposure to manganese (4.5 mg/m3) in the workplace compare to NIOSH time weighted average (Reference TWA= 1 mg/m3). The average blood Mn concentration was 2.745 and 274.85 �¼g/l for less than three months (n=35) and 3-12 months working experience (n= 35), respectively, it implies that there is a high accumulation of manganese in their blood. Risk assessment based on mutual evaluations of B-Mn and air-Mn seems to be valid in the understanding of workers' hazard. Our study indicates that B-Mn assessment by AAS may be a precise procedure for estimation of exposure condition based on working experience (more than 3 months).

Biography :

Email: seyedtaghim@gmail.com