Approaches to biomarker discovery for cancer screening

Molecular Biomarkers & Diagnosis

ISSN: 2155-9929

Open Access

Approaches to biomarker discovery for cancer screening

7th International Conference and Expo on Molecular & Cancer Biomarkers

September 15-16, 2016 Berlin, Germany

Anna Lokshin

University of Pittsburgh Cancer Institute, USA

Posters & Accepted Abstracts: J Mol Biomark Diagn

Abstract :

Despite considerable advancements, the development of effective cancer screening tools based on serum biomarker measurements has thus far failed to achieve a meaningful clinical impact. The incremental progress observed over the course of serum biomarker development suggests that further refinements based on novel approaches may yet result in a breakthrough. We will present complementary approaches that could considerable increase power of biomarker-assisted cancer screening including using alternative biofluids, such as urine, analysis of temporal biomarker dynamics prior to diagnosis, and using prospectively collected pre-diagnostic samples for biomarker discovery. Examples of utility of these approaches for development of ovarian and pancreatic cancers screening biomarkers will be presented.

Biography :


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Citations: 2054

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