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Cancer Science & Therapy

Cancer Science & Therapy

ISSN: 1948-5956

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Tissue Transplantation Scientific Journals

Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood or umbilical cord blood. It can be autologous (the patient's own stem cells are used), allogeneic (stem cells come from a donor) or syngeneic (from an identical twin). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed by radiotherapy or chemotherapy before transplantation. Infection and graft versus host disease are major complications of allogenic GCSH. Hematopoietic stem cell transplantation remains a dangerous procedure with many possible complications; it is reserved for patients with fatal diseases. As survival after the procedure increased, its use has spread beyond cancer to autoimmune diseases and hereditary skeletal dysplasia; including infantile malignant osteopetrosis and mucopolysaccharidosis. Many recipients of GCSH are patients with multiple myeloma or leukemia who would not benefit from or are already resistant to long-term treatment with chemotherapy

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Citations: 5332

Cancer Science & Therapy received 5332 citations as per Google Scholar report

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