Ankylosing spondylitis (AS), a common type of spondyloarthropathy, is a chronic inflammatory autoimmune disease that primarily affects the joints of the spine, causing severe chronic pain; moreover, in more advanced cases, it can cause a fusion of the spine. Significant advances in its pathophysiology and treatment have been made over the past decade. It has been suggested that immune cells and innate cytokines play a crucial role in the pathogenesis of AS, in particular the human leukocyte antigen (HLA) -B27 and the interleukin-23/17 axis. However, the pathogenesis of AS remains unclear. The present study examined the etiology and pathogenesis of AS, including genome-wide association studies and cytokine pathways. This study also summarized current pharmaceutical and surgical treatment with a discussion of potential future therapies.
Editorial: Journal of Spine
Editorial: Journal of Spine
Editorial: Journal of Spine
Editorial: Journal of Spine
Research Article: Journal of Spine
Research Article: Journal of Spine
Editorial: Journal of Spine
Editorial: Journal of Spine
Review Article: Journal of Spine
Review Article: Journal of Spine
Scientific Tracks Abstracts: Neurological Disorders
Scientific Tracks Abstracts: Neurological Disorders
Posters & Accepted Abstracts: Neurological Disorders
Posters & Accepted Abstracts: Neurological Disorders
Posters & Accepted Abstracts: Neurological Disorders
Posters & Accepted Abstracts: Neurological Disorders
Scientific Tracks Abstracts: Neurological Disorders
Scientific Tracks Abstracts: Neurological Disorders
Scientific Tracks Abstracts: Neurological Disorders
Scientific Tracks Abstracts: Neurological Disorders
Journal of Spine received 2022 citations as per Google Scholar report
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