Primary Aldosteronism | Open Access Journals

Journal of Surgical Pathology and Diagnosis

ISSN: 2684-4575

Open Access

Primary Aldosteronism

Primary aldosteronism (PA), also known as primary hyperaldosteronism or Conn 's syndrome, refers to excess hormone aldosterone output from the adrenal glands, resulting in low renin concentrations. Hyperplasia or tumors cause the abnormality. Many suffer from exhaustion, potassium deficiency, and high blood pressure that can lead to blurred vision, confusion, or headaches. Symptoms can include: muscle aches and fatigue , muscle spasms, kidney low back and flank pain, tremor, tingling sensations, numbness and frequent urination. Cardiovascular disorders such as stroke , myocardial infarction, kidney failure and irregular heart rhythms are complications. Many cases can be treated by surgical removal of the adenoma. For cases where only one is swollen a single adrenal gland can also be removed. For cases of both glands enlargement, diagnosis is usually performed with drugs known as aldosterone antagonists, such as spironolactone or eplerenone.

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