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Post-testicular Causes Scholarly Peer-review Journal | Open Access Journals
Research and Reports in Medical Sciences

Research and Reports in Medical Sciences

ISSN: 2952-8127

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Post-testicular Causes Scholarly Peer-review Journal

The post-testicular causes of infertility are generally due to the hindrance of sperm delivery or ejaculatory dysfunction. Azospermia is defined as the absence of sperm in the ejaculate. It has been identified in approximately 1 percent of all men and 10-15 percent of infertile males. Clinical management of obstructive azospermia depends on its cause and must also take into account any infertility factors coexisting in the female partner. The surgical management of obstructive azospermia differs with the site of obstruction and depends on the presence of pathological conditions, such as the absence of the vas deferens, the vasal obstruction and the obstruction of the ejaculatory duct. Congenital bilateral absence of vas deferens (CBAVD) is found in 1% of infertile men and 6% of men with obstructive azoospermia. There are two possible mechanisms responsible for this condition, such as mutations of the cystic fibrosis regulatory gene (CFTR) and anomalies in the differentiation of the mesonephric duct.

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