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Post-testicular Causes Peer-review Journals | Open Access Journals
Clinical and Medical Case Reports

Clinical and Medical Case Reports

ISSN: 2684-4915

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Post-testicular Causes Peer-review Journals

Post-testicular causes of infertility are generally due to the obstacle of sperm delivery or ejaculatory dysfunction. Azoospermia is defined as the absence of sperm in the ejaculate. It has been identified in approximately 1 percent of all men and in 10 to 15 percent of infertile males. The clinical management of obstructive azoospermia depends on its cause and also must take into account any coexisting infertility factors in the female partner. The surgical management of obstructive azoospermia differs with the site of obstruction and depends on the presence of pathological conditions, such as the absence of the vas deferens, vasal obstruction and ejaculatory duct obstruction. Congenital bilateral absence of the vas deferens (CBAVD) is found in 1 percent of infertile men and in up to 6 percent of men with obstructive azoospermia. There are two possible mechanisms responsible for this condition, as mutations of the cystic fibrosis transmembrane regulator gene (CFTR) and abnormalities in the differentiation of the mesonephric duct.

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