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Photodynamic Therapy Journals | Open Access Journals
Cancer Science & Therapy

Cancer Science & Therapy

ISSN: 1948-5956

Open Access

Photodynamic Therapy Journals

Photodynamic therapy (PDT) is based on the topical or systemic administration of a photosensitizer preferentially accumulated in a diseased target tissue. Irradiation of the diseased area triggers the production of toxic reactive oxygen species, subsequently leading to cell death. Furthermore, the photosensitizer’s ability to localize in diseases tissue can be used for the improved detection of disease because most of these molecules are intrinsically fluorescent. Most photosensitizers are based on porphyrins and phthalocyanines, though other chemical skeletons have been considered. Since its first description at the beginning of the 20th century, intensive research in PDT has provided profound insight into improved treatment modalities. Currently, PDT is developing intensively into other fields including bacterial inactivation and photochemical internalization.

Although not completely integrated into daily clinical practice in most areas, nowadays PDT represents of valid piece in today’s clinician’s toolbox for the curative and palliative treatment of several diseases, including head and neck cancer, age related macular degeneration, esophageal cancer, and skin cancer to name a few.

This special issue on photodynamic therapy is dedicated to the newest information in this research field. It should reflect a roundtable of the most proficient researches in photodynamic therapy. We expect an intensive debate and the latest findings on improved photosensitizers, innovative drug delivery strategies in PDT, and current and potential applications in clinical practice.

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Citations: 5332

Cancer Science & Therapy received 5332 citations as per Google Scholar report

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