Oxidative Stress Open Access Articles

Disturbance in the balance between the production of reactive oxygen species and antioxidant defenses is called oxidative stress. It is discussed in relation to its possible role in the production of tissue damage in diabetes mellitus . Several studies have suggested that oxidative stress could play a role in the pathogenesis of nonalcoholic fatty liver disease and more specifically in the transition from simple fatty liver disease to steatohepatitis. Some studies have suggested that, in addition to endotoxins, cytokines, hyperlipidemia and hyperinsulinemia, oxidative stress could play a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and more specifically in the transition from fatty liver disease simple and steatohepatitis (i.e. coexisting fatty liver disease with necrosis and inflammation of hepatocytes). Indeed, an excessive accumulation of fats in the liver, whatever the cause, is subject to attacks by reactive oxygen species (ROS), leading to lipid peroxidation with its cellular consequences. For example, an increase in lipid peroxidation has been documented in animal models, induced by drugs or food, while in genetic models of steatosis, such as ob / ob mice, there is an increase in the production of Mitochondrial ROS. Journal of Metabolic Syndrome is an open access peer-reviewed journal, which guarantees the quality of published articles. Each article must go through a single blind review process during which two independent review comments followed by a publisher decision are required to continue processing the article. This peer-reviewed journal on metabolic syndrome gives the world-class scientist barrier-free access to research. The journal article is sometimes called a scientific article, a peer-reviewed article, or a scholarly research article. Together, journal articles in a particular area are often called literature. Journal articles are most often primary research articles. However, they can also be review articles. These types of items have different purposes and requirements.