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Myocardial Ischemia Top Journals | Open Access Journals
Journal of Morphology and Anatomy

Journal of Morphology and Anatomy

ISSN: 2684-4265

Open Access

Myocardial Ischemia Top Journals

Myocardial ischemia is clinically indicated by transient ST-segment electrocardiogram (ECG) changes on exercise or pharmacological stress test and reversible perfusion defects on stress myocardial scintigraphy. Metabolic changes, including myocardial lactate production, coronary sinus oxygen desaturation, and pH reduction in the coronary sinus, are also important objective proof of myocardial ischemia. Myocardial release of lipid peroxide products in the coronary circulation is a marker of myocardial ischemia with a high sensitivity even for brief and/or mild myocardial ischemia. Myocardial phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy is another sensitive method to identify myocardial ischemia by measuring myocardial high-energy phosphates phosphocreatine and adenosine triphosphate. In addition to those ischemic metabolites, left ventricular wall motion abnormalities, detected by two-dimensional stress echocardiography, is a useful diagnostic method. Measurement of coronary blood flow is useful, but only provides information associated with myocardial ischemia. Positron-emission tomography (PET) allows the quantitative calculation of coronary blood flow. Magnetic resonance imaging (MRI) with intravenous infusion of contrast media can also be used for the quantification of myocardial blood flow.

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