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Cancer Science & Therapy

Cancer Science & Therapy

ISSN: 1948-5956

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Leydig-cell-tumors-top-open-access-journals.php

Sex stromal cell tumors constitute 5 to 8% of all ovarian neoplasms of which pure Leydig cell tumors constitute 0.1%. These tumors are most commonly found in the post-menopausal age group and patients experience rapid onset of excess androgen symptoms such as hoarseness of voice, clitoromegaly and hirsutism. We present a case of a 39-year-old woman who had been showing virilizing symptoms for 2 years. Serum testosterone levels were increased and CT revealed a homogeneously increasing mass of 2.8 cm in the right ovary. A unilateral oophorectomy was performed and sent for histopathological examination. On gross examination, the ovary revealed the presence of a well circumscribed grayish white tumor with multiple yellowish areas. Microscopy revealed features suggesting a pure Leydig cell tumor with reinke crystals. After the operation, the patient improved symptomatically. The unusual features observed in this case were a younger age at presentation and an insidious onset of symptoms. The presentation of a type of pure Leydig cell hilar tumor at such a young age is extremely rare.

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Citations: 5332

Cancer Science & Therapy received 5332 citations as per Google Scholar report

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