Immunotoxicology is the dysfunction of the immune system because of the exposure of organisms to extrinsic factors. The resistant system is a destination following exposure to a diverse group of xenobiotic including chemical pollutants, recreational drugs, ultraviolet radiation, and therapeutics. There is a well-established cause and effect relationship between the suppression of the immune response and reduced resistance to infections. Xenobiotic exposure may result in the stimulation of immune function. Xenobiotics can enforce as allergens and elicit hypersensitivity responses, or they can modulate hypersensitivity responses to other allergens. The immune dysfunction may take the form of immunosuppression or alternatively, allergy or autoimmunity, or any number of inflammatory-based diseases. Immunotoxicity can be noticed as one of several distinct immunopathologies that resistant allergic disease, immunodeficiency, and autoimmunity. In immunopathologies, the immune system responds to the agent as an allergen of low (hapten) or high molecular weight, which results in allergic contact dermatitis, food hypersensitivity, or respiratory hypersensitivity. In immunodeficiency, the immune system acts as a passive target for the agent and this may lead to increased incidence or severity of the infectious disease. Autoimmunity which is a break-down in self-tolerance occurs when an agent directly or indirectly induces an immune response to autologous constituents that result in pathological consequences. As the immune system plays a critical role in host resistance to disease as well as in normal homeostasis of an organism, identification of immunotoxic risk is significant in the protection of human, animal, and wildlife health.
Case Report: Immunochemistry & Immunopathology
Case Report: Immunochemistry & Immunopathology
Research Article: Immunochemistry & Immunopathology
Research Article: Immunochemistry & Immunopathology
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Posters & Accepted Abstracts: Medical Microbiology & Diagnosis
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Scientific Tracks Abstracts: Medical Microbiology & Diagnosis
Scientific Tracks Abstracts: Journal of Antimicrobial Agents
Scientific Tracks Abstracts: Journal of Antimicrobial Agents
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