Hereditary nonpolyposis colorectal cancer is the most frequent form of hereditary colorectal cancer. It is inherited as an autosomal dominant syndrome, as a result of defective mismatch repair proteins. Hereditary nonpolyposis colorectal cancer accounts for 2-5% of all colorectal carcinomas.There are a number of different inherited conditions that have a significant risk of colon cancer.It is estimated that 15–50% of colorectal cancers are familial. It can cause familial colorectal cancer even to a single gene, a combination of genes, or a combination of genetic and environmental factors . Typically these families have one or two members with a history of colorectal cancer or precancerous polyps.Inherited colorectal cancers are associated with a genetic mutation in a cancer susceptibility gene. Everyone inherits one responsiveness gene from each of their parents, making a total of two working copies of each gene. If a mutation in one copy of a cancer susceptibility gene is passed from the parent to their child, the child is predisposed (or has the potential) to develop cancer. Online Journals are scholarly and peer reviewed journals.
Posters & Accepted Abstracts: Cancer Science & Therapy
Posters & Accepted Abstracts: Cancer Science & Therapy
Accepted Abstracts: Alternative & Integrative Medicine
Accepted Abstracts: Alternative & Integrative Medicine
ScientificTracks: Cancer Science & Therapy
ScientificTracks: Cancer Science & Therapy
Posters & Accepted Abstracts: Journal of Trauma & Treatment
Posters & Accepted Abstracts: Journal of Trauma & Treatment
Posters & Accepted Abstracts: Journal of Nephrology & Therapeutics
Posters & Accepted Abstracts: Journal of Nephrology & Therapeutics
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