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Bone Marrow Library | Open Access Journals
Journal of Spine

Journal of Spine

ISSN: 2165-7939

Open Access

Bone Marrow Library

Multiple myeloma (MM) is a common hematologic condition that primarily affects older people, with a median age of diagnosis of approximately 65-70 years and a slight prevalence in males and African Americans. An abnormal growth of plasma cells within the bone marrow explains this condition, leading to interference with normal hemopoiesis and excessive production of abnormal monoclonal antibodies (paraprotein). Activation of osteoclasts in the surrounding bone tissue exposes the risk of pathological fractures and hypercalcemia. Molecular imaging modalities such as fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) or positron emission tomography / computed tomography (FDG-PET / CT) have recently emerged as reliable methods in initial staging. and planning the treatment of patients with MM. FDG is a glucose analog that accumulates in cells in proportion to its glycolytic activity: therefore, high metabolism neoplastic cells show increased absorption of FDG compared to normal surrounding tissue. The standardized absorption value (SUV) is a semiquantitative estimate of glycolytic activity in neoplastic lesions. Giorgio Treglia, Monitoring Response to Treatment in Patients With Multiple Myeloma: The Role of Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography

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Citations: 2022

Journal of Spine received 2022 citations as per Google Scholar report

Journal of Spine peer review process verified at publons

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