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Atherosclerosis Scholarly Journal | Open Access Journals
Cardiovascular Diseases & Diagnosis

Cardiovascular Diseases & Diagnosis

ISSN: 2329-9517

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Atherosclerosis Scholarly Journal

Atherosclerosis is the end result of hyperlipidemia and lipid oxidation and has constantly been a main motive of mortality in advanced international locations. it's far a ailment of vascular intima, in which all of the vascular machine from aorta to coronary arteries may be concerned and is characterized with the aid of intimal plaques. The term atherosclerosis is of Greek foundation, which means thickening of the intimal layer of arteries and accumulation of fat. Fatty material is located within the valuable core of the plaque, included via fibrous cap. The time period, atherosclerosis consists of two parts; atherosis (accumulation of fat followed by several macrophages) and sclerosis (fibrosis layer comprising easy muscle cells [SMC], leukocyte, and connective tissue). currently, atherosclerosis is a common disorder wherein fatty deposits referred to as atheromatous plaques appear in the internal layers of arteries. Formation of these plaques begins with the deposition of small ldl cholesterol crystals in the intima and its underlying smooth muscle. Then the plaques grow with the proliferation of fibrous tissues and the surrounding clean muscle and bulge inside the arteries and therefore lessen the blood waft. Connective tissue manufacturing by fibroblasts and deposition of calcium in the lesion reason sclerosis or hardening of the arteries. sooner or later, the choppy floor of the arteries outcomes in clot formation and thrombosis, which leads to the unexpected obstruction of blood glide.

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Citations: 427

Cardiovascular Diseases & Diagnosis received 427 citations as per Google Scholar report

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