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Articles On Menopause | Open Access Journals
Journal of Health & Medical Informatics

Journal of Health & Medical Informatics

ISSN: 2157-7420

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Articles On Menopause

As the menopause transition involves significant instability in estrogen levels, with intense irregular fluctuations, many researchers have focused on understanding the association between estrogen level and mood changes. As stated above, in longitudinal prospective studies, women who developed depression were more likely to possess increased variability in estrogen levels, particularly within the early to midperimenopause.30 absolutely the level of estrogen is not associated with risk, however. Some studies have used gonadotropin-releasing hormone (GnRH) agonists in order to induce menopausal changes in premenopausal women, so that measurement of hormones, evaluation for mood symptoms, and response to add-back hormone therapy are often more easily determined.35 during a group of healthy premenstrual women, without a psychiatric history, administration of a GnRH agonist didn't uniformly precipitate depressive symptoms.  Many women complain of changes in their cognitive function during the menopause transition, with the bulk reporting worsening of memory. Verbal memory (word list learning and recall), which women generally excel at when compared with men, is often the type of complaint noted.  In one study of 205 menopausal women, 72% reported some subjective memory impairment.41 Symptoms were more likely to be related to perceived stress or depressive symptoms than perimenopausal stage, but overall, cognitive symptoms were more prevalent early within the menopause transition. Aside from being bothersome, these symptoms raise women’s concerns regarding their risk for dementia; however, it remains unclear whether these symptoms correspond to an increased risk for more serious chronic issues.

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