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Journal of Brain Research

ISSN: 2684-4583

Open Access

Current Issue

Volume 4, Issue 3 (2021)

    Editorial Pages: 1 - 1

    The Attack and Survival Rate of Brain Tumor

    Vakshi Kuluchi

    Uncontrolled and abnormal cell growth in the brain is called a brain tumour. The space in our skull is restricted. Therefore, this extra growth inside our brain causes more pressure inside the skull, causing lifethreatening complications, and also damaging our brain. Tumours can be either benign or malignant. The benign ones are not cancerous and cannot spread to other parts of the brain or body. The malignant ones are cancerous, grow uncontrollably and can spread to other parts of the body.

    Editorial Pages: 1 - 1

    Brain Development in Adolescents

    Restivo Chango

    Adolescence is a transitional stage of physical and psychological development that generally occurs during the period from puberty to legal adulthood. Adolescence is usually associated with the teenage years, but its physical, psychological or cultural expressions may begin earlier and end later. For example, puberty now typically begins during preadolescence, particularly in females. Physical growth (particularly in males) and cognitive development can extend into the early twenties. Thus, age provides only a rough marker of adolescence, and scholars have found it difficult to agree upon a precise definition of adolescence.

    Awards 2021 Pages: 1 - 1

    Neurology and Neuroscience Medicine 2021

    Tran Birnbaum

    We are pleased to invite participants from All over the world to Attend international conference on “6th Global Congress on Neurology and Neurological disorders on Nov 11-12, 2021 New York, USA.

    Awards 2021 Pages: 1 - 1

    7 th World Congress on Psychotherapy 2021

    Morch Lack

    Psychology and Psychotherapist productively engaged in respective leading edge technology A poster is a method of presenting your research to an audience in a visual format. Conferences offer the unique opportunity to showcase your research in the poster format.

    Research Article Pages: 1 - 4

    A Neural Biomarker for Hallucinations: Medial Prefrontal Aberrations in Neural Connectivity Predict Self-Agency Deficits and Hallucination Severity in Schizophrenia

    Shalaila S. Haas, Leighton B.N. Hinkley, Melissa Fisher, Sophia Vinogradov, Srikantan Nagarajan and Karuna Subramaniam

    Prior studies have shown that the medial prefrontal cortex (mPFC) represents one neural substrate that mediates judgments of self-agency (i.e., the awareness that ‘I am the originator of my actions’). Patients with schizophrenia (SZ) manifest cardinal self-agency deficits that contribute to debilitating psychotic symptoms (e.g. hallucinations) and distort reality monitoring. This is the first study in which we examine across 2 SZ samples, the mPFC site that underlies self-agency deficits during an explicit reality-monitoring task (i.e., while subjects distinguish self-generated information from externally-derived information) in one SZ sample, and link Intrinsic functional connectivity (iFC) during rest within this a priori task-evoked self-agency seed with hallucination symptoms in a different SZ sample. In particular, we examined the iFC between the mPFC site that underlies self-agency deficits with all other brain regions in SZ using resting-state functional magnetic resonance imaging (fMRI). Resting-state fMRI data were collected from 32 SZ and 28 age, gender, and education-matched healthy control (HC) subjects. Functional connectivity maps were computed for each subject and compared between the HC and SZ groups. Within-group and between-group analyses revealed that aberrant iFC in this a priori-defined mPFC ‘self-agency seed’ predicted hallucination severity. The present findings reveal that the neural aberrations in this mPFC site represent one cardinal biomarker that underlies explicit self-agency deficits during a reality-monitoring task in one SZ sample that generalized to aberrant iFC differences in a different SZ sample and predicted worsening psychotic hallucinatory experiences. This region may represent a key neurobiological target for treatment avenues to improve hallucinatory symptoms.

    Volume 4, Issue 2 (2021)

      Case Report Pages: 1 - 2

      A Quick Review of the Brain; Adding to the "Eyes to Thighs" Protocol of Imaging for 18FDG-PET

      Riffat Parveen Hussain*

      Practices guidelines for PET-CT (Positron Emission Tomography with Computed Tomography) imaging for oncology dictates acquiring images from the base of the skull to mid-thigh (eye to thigh protocol), excluding imaging the brain. The accepted reason being given that brain, because of its high metabolism and exclusive glucose use, will “hide” lesions. Other positron emitting radionuclides have been rightly developed for its imaging, mainly Carbon-11 Methionine, Fluorine-18 Fluoroethyltyrosine (18F-FET), Fluorine-18 Dihydroxyphenylalanine (18F-FDOPA). The authors however argue that including the brain in the imaging protocol adds no extra radiation burden to the patient and adds on only a little on the acquisition time, however the benefit yield can add acknowledged benefits and sometimes change management paradigms.

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