Journal of Diabetic Complications & Medicine

Department of Pediatric Surgery, University of Pittsburgh, Children’s Hospital of Pittsburgh, Pittsburgh, USA

Publications

• Mini Review   
  In Patients with Type 2 Diabetes Mellitus, the Relationship between Vitamin D Status and Diabetic Foot
  Author(s): Xiangwei Xiao*
  
  One of the most severe and painful chronic complications of diabetes mellitus is diabetic foot (DF). Poor wound healing increases the risk of disability and death in diabetic patients1, 2 as well as the number of hospitalizations and lower limb amputations. The prevalence of DF has been estimated to be between 2.46 and 2.4 percent3 per year. Patients with healed foot ulcers have a higher than 50%4 incidence of recurrence after three years. As a result, diabetic foot is now a significant threat to public health.The regulation of bone turnover and the metabolism of calcium and phosphorus are both dependent on vitamin D, a pleiotropic steroid hormone. In addition, it is known to play a role in the inflammatory response, immune function, cell cycle regulation, and a number of chronic diseases, including diabetes and its complications5, 6. In addition, there is a co.. Read More»
  

  Abstract PDF