Research and Reports in Medical Sciences

Department of Chemistry, Southern University of Science and Technology, Shenzhen, China

Publications

• Opinion   
  Pancreatic Cancer: A Functional and Clinical Proteomic Investigation
  Author(s): Ruijun Tian*
  
  One of the most fatal forms of cancer is pancreatic ductal adenocarcinoma, with a median survival time of less than six months. PDAC patients have few therapeutic options, and surgery is still the most effective treatment, so early diagnosis is critical. The desmoplastic reaction of its stroma microenvironment, which actively interacts with cancer cells to orchestrate crucial aspects of tumorigenesis, metastasis, and chemoresistance, is one characteristic of PDAC. To decipher PDAC biology and develop intervention strategies, it is essential to conduct global research on cancer-stroma crosstalk. The rapid advancement of proteomics technologies over the past ten years has made it possible to profile proteins, post-translational modifications, and their protein complexes with an unprecedented level of dimensionality and sensitivity. Here, beginning with our ongoin.. Read More»
  DOI: 10.37421/2952-8127.2023.7.113

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