Hepatogastroenterology and Digestive Oncology Clinic, Grenoble-Alpes University Hospital, Grenoble, France
 Case Report   
								
																Hepatocellular Carcinoma Diagnosed in Bile Cytology: A Case Report and Review of the Literature 
																Author(s): Mariana Zaarour, Gael Roth, Pierre-Yves Eyraud, Nathalie Sturm and Diane Giovannini*             
								
																
						 Hepatocellular carcinoma (HCC) is the most common primary liver malignancy with a high mortality rate. The gold standard for making the 
  diagnosis is liver biopsy. However, this technique can sometimes be risky and contraindicated. Endoscopic retrograde cholangiopancreatography 
  is a largely used therapeutic procedure in hepatobiliary malignancies in case of jaundice. The latter offers also an easy access to bile samples 
  suitable for cytological examination. In addition to previously reported cases of HCC diagnosed by bile duct brushings, we are reporting the first 
  case of endobiliary HCC diagnosed by bile aspiration. We emphasize this rare and non-invasive cytological technique presenting advantages such 
  as cell block preparation and immunohistochemistry... Read More»
						  
																DOI:
								10.37421/1948-5956.2022.14.544															  
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