Journal of Diabetic Complications & Medicine

Russia

Publications

• Short Communication   
  Diabetes 2018: Interferon-Based Antiviral Treatment of Chronic Hepatitis C in Combination with Metformin in Patients with HCV-1 Genotype and Insulin Resistance : Olga Tarasova - University of Russia (RUDN University)
  Author(s): Olga Tarasova
  
    The efficacy of the antiviral therapy in patients with HCV genotype 1 infection rarely exceeds 40%.The main pre-treatment predictors of a sustained virological response (SVR) are: host genotype (in particular the CC genotype at the locus rs12979860 of the IL28B gene), viral genotype and pre-treatment viral load Other baseline factors providing a sustained response are: the right doses of Peginterferon (1.5 mcg/kg/week) and RBV (>10.6 mg/kg/ day), female gender, age less than 40 years, body weight (≤ 75 kg), elevated ALT (three-fold higher than upper limit of normal), the absence of bridging fibrosis or .. Read More»
  

  Abstract PDF