Journal of Cytology & Histology

ISSN: 2157-7099

Open Access

Maysam Jridi

Department of Internal Medicine, Rabta University Hospital Center, Tunis, Tunisia

  • Case Series   
    Clinical Features and Management of Langerhans Cell Histiocytosis: A Case Series
    Author(s): Tayssir Ben Achour*, Maysam Jridi, Ines Naceur, Monia Smiti, Fatma Said, Mohamed Habib Houman and Eya Azouz

    Background: Langerhans histiocytosis (LCH) is a rare hematopoietic disease characterized by clonal expansion of myeloid precursors differentiating into CD1a+/CD207+ histiocytes infiltrating different organs. The study aimed to report the clinical features such as the onset presentation and systemic lesions of LCH among Tunisian adult patients and the therapeutic management of the disease with onboard medications. Methods: A descriptive, retrospective and monocentric study taking place in the internal medicine department of Rabta University Centre. Results: The study included eight patients. The median age at the diagnosis was 35 years. The mean duration between the first symptoms and the diagnosis was 17 months. The first most consulted doctors were neurologists. The revealing symptoms were neurological in .. Read More»
    DOI: 10.37421/2157-7099.2023.14.689

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