Molecular and Genetic Medicine

Department of Science, University of California, Los Angeles, USA

Publications

• Mini Review   
  Genetic Screening for Inherited Familial Hypercholesterolemia in Cardiovascular Organ Transplants
  Author(s): Krista Ritchie*
  
  Familial hypercholesterolemia (FH) is an inherited condition that causes high levels of low-density lipoprotein cholesterol (LDL-C) in the blood. The condition is caused by mutations in genes responsible for regulating the metabolism of cholesterol in the liver. FH affects approximately 1 in 200 people worldwide, and is associated with a higher risk of premature cardiovascular disease (CVD), such as heart attacks and strokes. Heart transplantation is a life-saving procedure for patients with severe heart disease, but it is not without its risks. In particular, heart transplant recipients are at an increased risk for CVD, including accelerated atherosclerosis, which can lead to transplant failure and death. FH is a significant risk factor for accelerated atherosclerosis in heart transplant recipients, and managing cholesterol levels in these patients is critical to .. Read More»
  DOI: 10.37421/1747-0862.2022.16.587

  Abstract HTML PDF