Jun Kunisawa

Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research and Laboratory of Gut Environmental System, National Institutes of Biomedica, Japan

Publications

Research Article
Relationship between Human Gut Microbiota and Nutrition Intake in Hypertensive Discordant Monozygotic Twins
Author(s): Rie Tomizawa*, Jonguk Park, Natsuko Matsumoto, Koji Hosomi, Hitoshi Kawashima, Kenji Mizuguchi, Jun Kunisawa and Chika Honda

Background and Objectives: Intestinal bacteria digest substances, produce metabolites, and influence the host. Blood pressure increases with age, even in healthy people, and hypertension is said to affect one in four people worldwide. It is a major risk factor for stroke and stroke-related death. Although it is known that blood pressure is correlated with the ratio of Firmicutes and Bacteroides in gut microbiota and that the intake of peptides in fermented dairy products lowers blood pressure in humans, the relationship with the gut microbiota at the genus level is still inconsistent. Here, we aimed to examine the association between high blood pressure, gut microbiota, and nutrient intake by removing gender, age, and genetic effects. Materials and Methods: We selected hypertensive discordant Japanese monozygotic twins and confirmed their zygo.. Read More»
DOI: 10.37421/2167-1095.2021.10.297

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