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Molecular and Genetic Medicine

ISSN: 1747-0862

Open Access

Goit LN

Department of Cardiology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, P.R. China

Publications
  • Review Article   
    Atrial Fibrillation Associated with Wolf-Parkinson-White Syndrome in Patients with Brugada Syndrome: A Review
    Author(s): Goit LN*, Shaning Y and Wang X

    The Brugada syndrome is an autosomal dominant rare form of cardiac arrhythmia and has been associated with high risk of sudden cardiac death predominantly in younger male patients. It is associated with polymorphic ventricular arrhythmia/ventricular fibrillation, Supraventricular arrhythmia mainly atrial fibrillations and Wolf- Parkinson white syndrome. Patients can be presented with symptom like syncope, palpitation, sudden cardiac death and asymptomatically. Several pathogenic genes have been identified as associated with the disease but SCN5A is the most prevalent one. Several genetic mutations of different subunits of sodium, calcium and potassium channel have been involved. The management of Brugada syndrome and Wolf-Parkinson-White syndrome in patients with atrial fibrillation should be generally includes implantable cardioverter defibrillator and Rad.. Read More»

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Citations: 3919

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Molecular and Genetic Medicine peer review process verified at publons

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