Veterinary Science & Technology

ISSN: 2157-7579

Open Access

Dessie Abera

Department of Agriculture, Ethiopian Institute of Agriculture Research, Jima, Ethiopia

  • Review Article   
    A Compressive Review on Newcastle Disease Virus in Ethiopia
    Author(s): Tesfa Mossie* and Dessie Abera

    Newcastle disease is an acute viral disease that affects both domestic and wild bird species around the world. It is a costly and widespread disease in most poultry-producing countries, including Ethiopia. Newcastle disease virus is a member of the genus orthoavulavirus, species avian orthoavulavirus (AOAV-1), and a new subfamily Avulavirinae of the family Paramyxoviridae that causes Newcastle disease. The virus is a non-segmented, single-stranded, enveloped, negative-sense RNA virus. The virus's genome contains six open reading frames that encode six structural proteins and two non-structural proteins. The virus's two major surface glycoproteins are hemagglutinin-neuraminidase and fusion protein. The hemagglutinin-neuraminidase protein mediates virus binding to host target cells, whereas the fusion protein facilitates viral envelope fusion with the .. Read More»

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