Journal of Vasculitis

ISSN: 2471-9544

Open Access

Alasdair Coles

Addenbrooke’s Hospital, Cambridge University Hospitals, Robinson Way, Trumpington, Cambridge CB2 0AX, UK

  • Case Report   
    When No More Investigations are Left: A Probable Case of Primary Angiitis of the Central Nervous System
    Author(s): Minesh Patel, Mohamed Rashad Ramali*, Saad Ahmed, Edward Needham, Imtiaz Ahmed and Alasdair Coles

    Primary angiitis of the CNS (PACNS) is a distinct form of cerebral vasculitis, the former being confined to the central nervous system (CNS) with no systemic involvement. Diagnosing PACNS is challenging due to its varied presentation and rarity. We describe a case highly suggestive of PACNS which despite extensive investigation could not be confirmed even on histology but responded to immunosuppression. We present a 69-year old man who presented to the emergency department (ED) with acute confusion. Initial magnetic resonance (MR) imaging of the head had shown ischaemic infarcts and haemorrhages. Cerebrospinal fluid (CSF) analysis and serological work-up had ruled out a systemic vasculitis and an infectious disease to account for the presentation. Computerised tomography (CT) angiography nor digital subtraction angiography had reported any evidence of vasculopa.. Read More»
    DOI: 10.37421/2471-9544.2023.9.175

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