Journal of Clinical Case Reports

ISSN: 2165-7920

Open Access

Wang Y

Qianfoshan Hospital Affiliated to Shandong University School of Medicine,
No. 16766 Jingshi Road, Jinan, Shandong

  • Case Report
    Ten Cases of Hepatic Sinuses Obstruction Syndrome Caused by Sedum Uizoon
    Author(s): Wang X and Wang YWang X and Wang Y

    Hepatic sinuses obstruction syndrome (HSOS) also known as hepatic venule syndrome, refers to the injury of central lobe and sub-lobular vein of hepatic lobule, resulting in intrahepatic posterior sinus portal hypertension caused by lumen stenosis or occlusion. Currently the pathogenesis is not clear. It may be related to the drug, immunity and inflammation of the liver vein endothelial cells. The clinical manifestations are hepatomegaly, right upper abdominal pain, jaundice and ascites, with a high risk of mortality and poor prognosis for characteristics. Occurs because of cytoreductive therapy prior to hematopoietic stem cell transplantation (HSCT), adjuvant or neoadjuvant chemotherapy containing oxaliplatin for colorectal carcinoma metastatic to the liver and treated by partial hepatectomy, taking herbal remedies containing pyrrolizidine alkaloid and the autosomal recessive conditio.. Read More»
    DOI: 10.4172/2165-7920.10001135

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