GET THE APP

..

Cancer Science & Therapy

ISSN: 1948-5956

Open Access

Sunita N Dyavanagoudar


Basav Nivas, Jayanagar, Dharwad, Karnataka
India

Publications
  • Review Article
    Oral Submucous Fibrosis: Review on Etiopathogenesis
    Author(s): Sunita N DyavanagoudarSunita N Dyavanagoudar

    Summary data from recent epidemiological studies provide overwhelming evidence that areca nut is the main aetiological factor for OSF. Commercially freeze dried products such as pan masala, Guthka and mawa have high concentrates of areca nut per chew and appear to cause OSF more rapidly than by self prepared conventional betel quid that contain smaller amounts of areca nut. It is logical to hypothesize that the increased collagen synthesis or reduced collagen degradation as possible mechanisms in the development of the disease. These chemicals appear to interfere with the molecular processes of deposition and/or degradation of extracellular matrix molecules such as collagen. In vitro studies on human fibroblasts using areca extracts or chemically purified arecoline support the theory of fibroblastic proliferation and increased collagen formation that is also demonstrable histologicall.. Read More»

    Abstract PDF

Relevant Topics

Google Scholar citation report
Citations: 3968

Cancer Science & Therapy received 3968 citations as per Google Scholar report

Cancer Science & Therapy peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward