Journal of Clinical Case Reports

ISSN: 2165-7920

Open Access

Philippe Desmarais

Centre Hospitalier de l’Université de Montréal,
Montréal, Québec

  • Case Report
    Fluctuating Hearing Loss Responding to Corticosteroids: A Case of Cogans Syndrome Concomitant with Crohns Disease
    Author(s): Philippe Desmarais and Mikhael LaskinePhilippe Desmarais and Mikhael Laskine

    Hearing loss has a broad differential diagnosis. Hearing impairment responding to corticosteroids is suggestive of an underlying autoimmune cause. We report a rare case of Cogan’s syndrome in a 28-year-old woman with no previous personal medical history. She had experienced two years of fluctuating hearing loss and bilateral keratitis that would respond to high-dose prednisone prescribed by her otorhinolaryngologist. We performed a complete work-up and ruled out most common causes of autoimmune inner ear diseases. Patient was diagnosed with Cogan’s syndrome based on clinical findings and prescribed corticosteroid-sparing immunosuppressive medication. During follow-up, she developed worsening fatigue, new onset anemia, and melena. Endoscopic and pathologic findings were diagnostic of Crohn’s disease. This case emphasizes the high prevalence of concomitant autoimmune d.. Read More»
    DOI: 10.4172/2165-7920.1000810

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