Journal of Clinical Case Reports

Mathieu Valla

Publications

• Case Report
  A Marantic Endocarditis Complicating a Metastatic Gastric Adenocarcinoma Initially Resistant to Low-molecular Weight Heparin: A Case Report
  Author(s): Raffaele Longo, Anne Béatrice Notarantonio, Clémence Elias-Matta, Christian Platini, Nada Eid, Aude Zanutto, Mathieu Valla, Laurent Hennequin, Philippe Quétin and Khalifé KhaliféRaffaele Longo, Anne Béatrice Notarantonio, Clémence Elias-Matta, Christian Platini, Nada Eid, Aude Zanutto, Mathieu Valla, Laurent Hennequin, Philippe Quétin and Khalifé Khalifé
  
  Background: Marantic endocarditis is a rare paraneoplastic syndrome which results from an hypercoagulate state. It can be associated with several tumors, particularly gastric cancer, and histology of adenocarcinoma. Mucines secreted by adenocarcinoma contribute to the activation of the coagulation pathway. Case presentation: We present the case of a patient with a marantic endocarditis complicating a metastatic gastric adenocarcinoma. He was hospitalised for a thoracic pain. At the physical examination, we found swelling, redness, and warmth of the right lower limb, suspected for a deep vein thrombosis that was confirmed at the echo doppler ultrasound. CT scan documented a severe bilateral pulmonary embolism, a splenic infarction, and multiple liver metastases. Laboratory tests were normal. Despite a Low-Molecular Weight Heparin (LMWH) treatment, the .. Read More»
  DOI: 10.4172/2165-7920.1000633

  Abstract PDF