Cancer Science & Therapy

Grace Kho Dy

Publications

• Commentary
  Emerging Systemic Therapeutic Approaches for Personalized Medicine in Squamous Cell Carcinoma of the Lung
  Author(s): Grace Kho DyGrace Kho Dy
  
  During the past decade, a number of novel agents developed for the treatment of advanced NSCLC had, by coincidence, shown survival benefit predominantly among patients with nonsquamous histology, namely pemetrexed (anti-folate), bevacizumab (VEGF pathway inhibition), erlotinib/gefitinib (EGFR receptor tyrosine kinase inhibitors) and crizotinib (ALK receptor tyrosine kinase inhibitor. This has sparked a heightened interest in discovering key molecular aberrations that may be relevant for the treatment of squamous cell carcinoma (SCC) of the lung, a histologic subtype that represents approximately 25% of lung cancer cases diagnosed globally. This article highlights the most promising recent discoveries and targeted agents in development that may be relevant for the treatment of SCC of .. Read More»
  DOI: 10.4172/1948-5956.S11-003

  Abstract PDF