University Hospital UZ Brussel,
Brussels
Belgium
Research Article
Impact of Management Changes on Loco-Regional Control of Breast Carcinoma: A 30-year Single Institution Experience Breast Cancer: Basic and Clinical Research
Author(s): Geertje Miedema, Mia Voordeckers, Christel Fontaine, Marian Vanhoeij, Guy Storme and Mark De RidderGeertje Miedema, Mia Voordeckers, Christel Fontaine, Marian Vanhoeij, Guy Storme and Mark De Ridder
Purpose: This institutional-based study aims to reflect changes in diagnosis, surgery, radiotherapy, systemic therapy by retrospectively analysing treatment modalities and outcome during the past 30 years of breast cancer. We hypothesized these changes result in better outcome.
Material and methods: 2990 women are included, aged 18–95, no previous cancer, unilateral stage I-III primary breast tumors, breast-conserving surgery (BCS) or mastectomy (ME), postoperative radiotherapy (RT) and where indicated systemic treatment. Patients were divided in 3 cohorts stratified by year of diagnosis: 1984-1991, 1992- 1999 and 2000-2008. The interval of cohorts was based on institutional changes in systemic regimens.
Results: Over time, median age at .. Read More»
Journal of Oncology Medicine & Practice received 142 citations as per Google Scholar report
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 