Organ Transplantation and Advanced Technologies, Surgery Oncology Unit, 
Italy						                            
                            
						
 Case Report
												Cutaneous Rosai-Dorfmann Disease in Autistic Patient: Is there a
Pathogenetic Correlation? 						
Author(s): Caglia  P, Tracia  A, Borzi  L, Lucifora  B, Tracia  L, Spataro  D and Amodeo  CCaglia  P, Tracia  A, Borzi  L, Lucifora  B, Tracia  L, Spataro  D and Amodeo  C             
						
												
				 Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a benign disorder of histiocyte proliferation that usually affects the lymph nodes. Purely Cutaneous Rosai-Dorfman Disease (CRDD) is a rare extranodal variant that is strictly limited to the skin. We report a patient with of cutaneous rosai-dorfman of the abdominal wall with a past medical history of autism spectrum disorders. Autism is surely a complex disease and the most prevailing opinion is that it is a neuro-immune disorder. Both the diseases are considered strictly correlated to the immune disorders and the immunodeficiency might play an important pathogenetic role. A brief review of the literature of CRDD is also provided.
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												DOI:
												 10.4172/2165-7920.1000312 
																	  
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