Austria						                            
                            
						
 Case Report
												A Case of Eight-and-a-Half-Syndrome as a Presenting Manifestation of
Late Onset Multiple Sclerosis 						
Author(s): Bsteh G, Boesch S, Deisenhammer F, Berger T, Poewe W and Nocker MBsteh G, Boesch S, Deisenhammer F, Berger T, Poewe W and Nocker M             
						
												
				 We describe a 74-year-old woman presenting with right Internuclear Ophtalmoplegia (INO), horizontal gaze palsy and ipsilateral peripheral facial nerve palsy known as eight-and-a-half-syndrome. MRI and CSF findings led to diagnosis of Clinically Isolated Syndrome (CIS). One month later, the patient suffered acute myelitis. Our patient represents a rare case of late onset Relapsing-Remitting Multiple Sclerosis (RRMS) presenting with an eight-and-a-half-syndrome. Apart from the clinical rarity of eight-and-a-half-syndrome, this case serves as a reminder that MS can occur in every period of life and should be considered in differential diagnosis irrespective of age at onset of neurological symptoms [1].
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												DOI:
												 10.4172/2165-7920.1000845 
																	  
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report