GET THE APP

..

Medicinal Chemistry

ISSN: 2161-0444

Open Access

Volume 11, Issue 9 (2021)

Mini Review Pages: 1 - 3

Recent Advances in Natural Product-Based NF-κB Inhibitors as Anticancer and Anti-Inflammatory Agents

Arijit Nandi and Anwesha Das

Certain activation of signaling pathways plays a great role in cancer pathogenesis and the growth and progression of the tumor cells. Among the several signaling pathways intensively entangled in cancer progression, NFâ??κB is one of the important pathways which are actively explored by researchers [1]. This B cell-specific transcription factor NFâ??κB family is first discovered by David Baltimore’s group. It contains five different DNAbinding proteins which are actively involved in the formation of homodimers and heterodimers. NFâ??κB proteins are key regulators of innate and adaptive immune responses that can accelerate cell proliferation, inhibit apoptosis, promote cell migration and invasion, and stimulate angiogenesis and metastasis [2]. The normal activation of the NFâ??κB is necessary for the survival of the cells and immunity, its deregulation can results development of cancer and multiple inflammatory diseases. Therefore NFâ??κB is one of the major targets of anticancer and anti-inflammatory molecule development.

Short Communication Pages: 1 - 1

Kejia Jessy*

An ongoing condition is a human medical issue or illness that is tenacious or in any case durable in its belongings or a sickness that accompanies time. The term ongoing is regularly applied when the course of the sickness goes on for over 90 days. Normal constant infections incorporate joint pain, asthma, malignancy, persistent obstructive pneumonic illness, diabetes, Lyme sickness, immune system illnesses, hereditary issues and some popular illnesses like hepatitis C and AIDS. A sickness which is long lasting on the grounds that it closes in death is a terminal ailment. It is conceivable and not sudden for an ailment to change in definition from terminal to ongoing

Short Communication Pages: 1 - 2

Kejia Jessy*

Pharmaceutical fabricating is the cycle of modern scale combination of drug drugs as a feature of the drug business. The interaction of medication assembling can be separated into a progression of unit activities, like processing, granulation, covering, tablet squeezing, and others. While a research facility may utilize dry ice as a cooling specialist for response selectivity, this interaction gets confounded on a mechanical scale. The expense to cool a run of the mill reactor to this temperature is enormous, and the thickness of the reagents regularly likewise increments as the temperature bring down, prompting troublesome blending. This outcome in added expenses to mix more enthusiastically and supplant parts all the more frequently or it's anything but a non-homogeneous response

Short Communication Pages: 1 - 2

Kejia Jessy*

Substance science is a logical order traversing the fields of science and science. The control includes the use of substance methods, investigation, and frequently little particles created through engineered science, to the examination and control of natural frameworks. Maybe than normal science, which incorporates the examination of the study of biomolecules and rule of biochemical pathways inside and between cells, compound science oversees science applied to science mix of biomolecules, re order of natural systems.

Short Communication Pages: 1 - 1

Kejia Jessy*

Clinical drug science is a claim to fame part of compound sciences, which comprises of restorative science with extra preparing in clinical parts of translational sciences and medication. Normally this includes comparable chief preparing as in everyday medication, where assessment of and connection with the patients are a fundamental piece of the preparation.Regularly understudies in clinical drug science utilize similar educational program as clinical understudies, however work in therapeutic and natural science after and during the hypothetical/ early clinical examinations.

Google Scholar citation report
Citations: 6627

Medicinal Chemistry received 6627 citations as per Google Scholar report

Medicinal Chemistry peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward