Journal of Oncology Translational Research

Programmed cell death, also known as apoptosis, is a tightly regulated cellular process that plays a critical role in development, tissue homeostasis, and the elimination of damaged or unwanted cells. Apoptosis involves a series of molecular events orchestrated by a complex network of signalling pathways. Dysregulation of programmed cell death can have profound implications in various pathological conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. Understanding the mechanisms and molecular players involved in apoptosis has significant implications for the development of novel therapeutic strategies targeting cell death pathways. This abstract provides an overview of the concept of programmed cell death, its molecular mechanisms, regulatory factors, and its relevance in human health and disease.

Genomic profiling is a powerful technique that involves the comprehensive analysis of an individual's genome to identify genetic alterations and variations. With the advent of high-throughput sequencing technologies, genomic profiling has become an indispensable tool in various fields, including cancer research, personalized medicine, and population genetics. This technique provides valuable insights into the genetic landscape of individuals, allowing for the identification of disease-associated mutations, prediction of treatment response, and understanding of disease mechanisms. This abstract provides an overview of genomic profiling, including its methodologies, applications, and implications in various fields of research and clinical practice.