Cardiovascular Diseases & Diagnosis

ISSN: 2329-9517

Open Access

Volume 9, Issue 3 (2021)

Research Article Pages: 1 - 5

Computed Tomography Coronary Angiography added to Standard Care with High-Sensitivity Cardiac Troponin for Acute Chest Pain

Jae Gyung Kim, Eun Ho Choo, Dongjae Lee, Chan JK, Hyo SA, Jong Min Lee and Hui-Kyoung J

European Society of Cardiology (ESC) 0/3-h algorithm using high sensitivity cardiac troponin (hs-troponin) is recommended to detect acute myocardial infarction (MI) for patients with acute chest pain. As hs-troponin may be less specific, we assessed the usefulness of coronary computed tomography angiography (CCTA) in addition to standard care for patients with acute chest pain. We investigated 695 patients who visited the emergency department for acute chest pain and performed serial hs-troponin T and CCTA. Obstructive coronary artery disease (CAD) on CCTA was defined as >=50% stenosis. The primary outcome was the occurrence of MI within 30 days. According to ESC 0/3-h algorithm, patients were categorized into rule-out (425, 61.2%), rule-in (155, 22.3%), and observe group (115, 16.5%). Eighty-one patients (11.7%) were diagnosed with MI. Two hundred ten patients had obstructive CAD on CCTA. The addition of obstructive CAD on CCTA to ESC 0/3-h algorithm improved the diagnostic accuracy for MI (area under the curve: from 0.85 to 0.911, p=0.003). Even for the rule-in and rule-out patients, the specificity (from 78.9% to 94.5%) and positive predictive value (from 32.1% to 62.8%) were significantly improved after the addition of CCTA to ESC 0/3-h algorithm. Half of the patients in the rule-in group did not undergo invasive coronary angiography based on CCTA findings without further MI events. CCTA added to the serial hs-troponin may improve the prediction of MI in patients with acute chest pain.

Research Pages: 1 - 7

Assessment of Right Ventricular Function after Acute Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

Mahmoud Abdelsabour, Khaled Saber, Doaa Ahmed Fouad

Background: The effect of the different sites of acute ST-elevation myocardial infarction (STEMI) and left ventricular (LV) dysfunction on systolic and diastolic right ventricular (RV) function is still unclear. In this study, we aimed to assess the effect of primary percutaneous coronary intervention (PPCI) on RV function using echocardiography. Methods: One hundred and seven consecutive patients with first episode of acute STEMI were enrolled in this study with echocardiographic imaging obtained both within 24 hours and 6 months after successful PPCI. Patients were divided into two groups, anterior (45%) and non-anterior STEMI (55%) based on significant ST-segment elevation. Results: At presentation, TAPSE (tricuspid annular plane systolic excursion) and FAC (Fractional area change) were significantly lower in nonanterior vs. anterior group (1.9 ± 0.44 vs. 1.57 ± 0.47cm, p=0.005), (40.4 ± 7.5 vs. 34.6 ± 9%, p=0.001). No significant differences of tricuspid E/A, E/é ratio between both groups were detected while a negative correlation between LV-EF (ejection fraction) and TAPSE was recorded (r=0.24). At follow up, the anterior group showed significant improvement of RV-MPI (myocardial performance index) and LV-EF (p value=< 0.01 and 0.08, consecutively) but not of RV-DF (diastolic function). In non-anterior group, RV recovered significantly regarding FAC, TAPSE, RV-MPI and tricuspid E/é (p value=< 0.01 for all) with no improvement of LV-DF or LV-EF irrelevant of the infarction site. LV-EF showed negative correlation with LV-DF at baseline (r=0.22) and follow up (r=0.4), and with tricuspid E/é at follow up (r=0.4). Additionally, positive correlation between LV-DF and both tricuspid E/é and grades of mitral regurgitation (MR) at baseline and follow up (r=0.37, 0.28 respectively). Conclusion: RV dysfunction can be detected in both anterior and non-anterior STEMI patients at presentation which is more prominent in the nonanterior group. At follow up successful primary PCI patients exhibited recovery of RV systolic function in both groups, while impairment of LV-DF was noted irrelevant of the infarction site. Assessment of RV systolic and diastolic function using echocardiography is useful, rapid and feasible method that can be done initially and at follow up to all STEMI patients.

Editorial Pages: 1 - 1

Walnuts have been Shown to be Effective in the Treatment of Cardiovascular Disease in a Study

Duraisamy Balaguru

According to research from a randomised controlled study, walnuts have the potential to prevent significant risk factors for heart disease, and that ‘people who eat walnuts on a daily basis can have a lower risk of heart disease.' According to research from a randomised controlled study, walnuts have the potential to prevent significant risk factors for heart disease, with people who eat walnuts on a daily basis having a lower risk of heart disease than those who do not.

Editorial Pages: 1 - 1

Heart Disease is more likely in Women who have had Complications During Pregnancy

Duraisamy Balaguru

Up to 50% of women experience high blood pressure before they reach the age of 60, but the symptoms, such as hot flushes and palpitations, are often due to menopause. A recent research claims that risks during pregnancy and early menopause increase women's potential risk of heart disease. The results were published in the journal 'European Heart Journal.' In the research, cardiologists, gynaecologists, and endocrinologists provided advice on how to help middle-aged women avoid future heart problems. The study concluded that "physicians could increase their detection of hypertension in middle-aged women."

Editorial Pages: 1 - 1

Sleeping with Abnormal Blood Pressure Increases the Risk of Heart Failure and Stroke, according to a New Report

Duraisamy Balaguru

According to new research, people who have high blood pressure while sleeping are more likely to develop potential cardiovascular disease, especially heart failure, even if their blood pressure during the day is normal. The findings were published today in Circulation, the flagship publication of the American Heart Association. In-office and daytime blood pressure tests are widely used by health care providers to assess a patient's hypertension medication requirements and dosages. Many patients, however, may have nocturnal hypertension, or elevated blood pressure while sleeping, which goes unnoticed. The study participants were told to sleep or rest during the night and continue with their normal activities during the day. In a diary, they documented their everyday tasks, as well as their sleep and wake times. Almost every participant took 20 automatic blood pressure readings during the day and seven at night. Patients self-reported the moment they fell asleep and woke up to assess night-time measurements. All other readings were taken throughout the day.

Google scholar citation report
Citations: 303

Cardiovascular Diseases & Diagnosis received 303 citations as per google scholar report

Cardiovascular Diseases & Diagnosis peer review process verified at publons

Indexed In

arrow_upward arrow_upward