Journal of Clinical Case Reports

ISSN: 2165-7920

Open Access

Volume 11, Issue 6 (2021)

Case Report Pages: 1 - 3

Anagrelide Treatment and Congestive Heart Failure in the COVID-19 Era: A Case Report

Corsini Anna*, Fiorini Giulia, Zuffa Elisa, Borghi Claudio and Galie Nazzareno

DOI: 10.37421/2165-7920.2021.11.1444

Background: This case report emphasises the importance of differential diagnosis in dilated cardiomyopathy and the frequent misdiagnosis of congestive heart failure in the COVID-19 era.

Case presentation: A patient with Polycythaemia Vera (PV) and no history of cardiac disease developed dyspnoea and radiological signs of pulmonary congestion. He was then treated as a suspected COVID-19 patient. However, echocardiogram showed biventricular dysfunction and severely reduced Left Ventricular Ejection Fraction (LVEF) (22%) without regional wall motion abnormalities. We hypothesised drug-related cardiotoxicity.

Conclusion: Particular attention should be paid to patient admitted to Emergency Department (ED) with respiratory symptoms and clinical signs of congestion in order to correctly differentiate COVID-19 related respiratory disease from cardiogenic dyspnoea. Cardiotoxicity should always be ruled out in dilated-hypokinetic cardiomyopathy.

Case Report Pages: 1 - 2

A First Case of Adrenomyeloneuropathy with Mutation R152C: A Case Report with Literature Review

Malek Mansour, Rania Ben Aoun, Maroua Melliti*, Amel Kacem, Meriem Mselmani, Ridha Mrissa and Jamel Zaouali

DOI: 10.37421/2165-7920.2021.11.1445

X-linked Adrenoleukodystrophy (X-ALD) is a rare genetic disorder responsible of accumulation of Very Long Chain Fatty Acids (VLCFAs) which accumulate in the central nervous system, adrenal cortex and testes. Various mutations have been identified, the X-ALD mutation database catalogs 2707 (last updated on 04-03-2019) with 61% of missense mutations. This paper reports on a first case of AMN with R152C mutation in ABCD1 gene.

Case Report Pages: 1 - 2

Ruptured Hematosalpinx: An Unconventional Cause of Hemoperitoneum in Early Pregnancy

Carrington Kambasha*, Neelam Prasad, Pradumna Jamjute and Haissam Moukarram

DOI: 10.37421/2165-7920.2021.11.1446

Hemoperitoneum with an adnexal mass in reproductive age group women points to a life-threatening differential diagnosis of a ruptured ectopic pregnancy. Rarely isolated tubal pathology such tubal torsion with hematosalpinx may mimic such a picture and the diagnosis is difficult in hemodynamically compromised patients. This is a case report of isolated hematosalpinx without torsion in early pregnancy which was histologically confirmed following surgical management.

Case Report Pages: 1 - 2

Radiosugery with CyberKnife in Primary Orbital MALT Lymphoma: A Case Report

Vasko Graklanov*, Popov Valery and Grudeva-Popova Janet

DOI: 10.37421/2165-7920.2021.11.1448

MALT lymphoma constitutes one half of all orbital malignancies. Ocular adnexal lymphoma of MALT-type (OAML) may affect critical structures in the orbit and can become therapeutic challenge. Surgery, radiotherapy or chemotherapy, alone or in combined modalities can be used as treatment options based on the individual patient variables as well as the site, stage and surgical accessibility of the OAML. This case confirms that radiosurgery with CyberKnife is an effective and safe therapeutic option in patients with OALM reducing the collateral damage to a minimal rate.
Case Series Pages: 1 - 5

Septic Shock Complicated with Limb Ischemic Necrosis: Three Case Reports and their Review of Literature

Zhenggong Li*

DOI: 10.37421/2165-7920.2021.11.1450

Purpose: Limb ischemic necrosis is a very rare but severe condition that generally leads to amputation in septic shock. Our aim is to review the risk factors for development of limb ischemic necrosis in ICU patients requiring vasopressor support and draw the attention of doctors.

Methods: A retrospective review of clinical information and photographs in 3 septic shock patients, including APACHII scores, dose of norepinephrine, time of ischemic necrosis and final outcome from July 2001 to June 2020 at a single intensive care unit


Results: All of the three patients had high APACHE II score, obvious coagulation dysfunction and severe hypotension on admission; In order to maintain the target blood pressure, the dose of norepinephrine range from 0.36 to 7.27 μg/kg/min; Case 2 and 3 had a higher average dose and length of NE treatment when comparing to case 1. Finally, case 1 survived but undergone amputation, case 2 and case 3 died.

Conclusion: Septic shock with limb ischemic necrosis is a very serious complication and may indicate a poor prognosis. As an ICU doctor, we should pay attention to the complication in our clinical practice which can greatly affect patient’s quality of later life.

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