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Clinical and Medical Case Reports

Open Access

Volume 5, Issue 9 (2021)

Short Communication Pages: 1 - 1

Interactions between Plant, Microbe and Insects

Mousik Sabito*

DOI: 10.37421/cmcr.2021.5.167

Using helpful soil bacteria to help increase in a good way plant growth and reduce pests is a promising direction for able to last the planet farming. However, we need to understand the related to how living things affect their environment basis of these interactions in order to identify those with the greatest possible ability to have a hit. To do this, we need to support the complex difficulty of coming from or caused by more than one thing experiments to watch the strength of benefits across number or thing that changes surrounding conditions. I briefly review the recent books on plant-bacteria-insect interactions across changing surrounding conditions, focusing on those using many factors. I finish by exploring related to how living things affect their environmental research approaches and coming from or caused by more than one thing experimental designs that can be used to simplify the study of plant-bacteria-insect interactions.

Short Communication Pages: 1 - 1

Using Rat Ultrasonic Vocalization to Study the Neurobiology of Emotion

Ushmayi Eresha*

DOI: 10.37421/cmcr.2021.5.168

The use of ultrasonic speaking as AN experimental tool for learning emotional states in rodents has light-emitting diode to AN inflated understanding of the essential science of have an effect on additionally because the development of recent determining the matter with a human health and medically useful things for the treatment of major issues with dominant emotions. At the behavioural level, the foundations that govern the generation of associated with emotions 'feeling' states area unit a bit like those of the psychonomics of associated with hearing, seeing, smelling, etc. perception. Feelings of affection, hate, fear, etc. area unit brought-out principally in response to active social things that cause reactions or that increase activity. At the nerve-related level, the coordinated expression of associated with emotions responses within the middle half anterior cortex is planned by sort of a steady drumbeat activity, that is started and maintained by a spread of for under a brief time and long junction flexibility processes.

Research Article Pages: 1 - 5

Curcumin (Curcuma Longa) and Quercetin Nanoparticles as Anticancer Agents for HepG2 and HCT116 Human Cell Lines

Soheir N. Abd El-Rahman* and Raafat N. Sandak

DOI: 10.37421/cmcr.2021.5.166

Curcumin and quercetin are very poor water solubility, it could be these bio products useful and important in condition therapy related with cancer, oxidative stress and can used it to develop functional foods and to improve the foods shelf life. The objective was to prepare Curcumin and quercetin nanoparticles (CurNPs and QurNPs) give highly stable and soluble in water. The DPPH radical scavenging activity, HepG2 and HCT116 human cell lines (human cancer liver and colon) and antimicrobial of CurNPs and QurNPs were determined. The results showed that the CurNPs and QurNPs had the highest DPPH free radical scavenging activity at concentrate 1000 µg/ml were 94.91 and 98.11%, these results equal or nearly from ascorbic acid as at positive control at the same concentrate was 98.69%. CurNPs and QurNPs were significantly increased cell cytotoxicity, from the minimum to maximum concentrations ranging from 6.25 to100 µg/ml in HepG2 human cell lines (human cancer liver) which inhibition these cells at concentrate 100 µg/ml were 87.434 and 87.848% and the viability cells were 12.566 and 12.152%, IC50 = 31.15, 5.80, respectively. Meanwhile, the HCT116 human cell lines (human cancer colon), results found that the inhibition cells were 93.112 and 92.893% and the viability cells were 7.888, 7.1075 and IC50 = 22.65, 6.68, respectively. The highest inhibition zone in gram-positive bacteria than gram-negative bacteria was at 100µg/ml. Therefore, it could be recommended that drugs within nanoparticles enhance the entry of drugs within tumor tissues in vivo and antimicrobial by the enhanced retention and permeation effect.

Mini Review Pages: 1 - 1

Utility of a Clinical Diagnostic Tool for the Diagnosis of Tuberculosis

Vatsyte Preeck

DOI: 10.37421/cmcr.2021.5.169

Dangerous respiratory organ sickness like Tuberculosis (TB) remains a major public health issue worldwide particularly in developing countries, wherever the sickness is usually found in this place and effective TB sickness-identifying yet as treatment-watching tools square measure serious things that block or stop alternative things to defeating the disease. Detection of one thing that causes disease-specific associated with process and exploitation food pathways offers a possible alternative option to current ways, that target microorganism growth, microorganism super molecule creating one thing clear, or detection of host unable to be injured response to the one thing that causes sickness. associated with process and exploitation food pathway detection might give quick and effective new tools for TB which will improve TB deciding the matter with a personality's health for kids and HIV infected patients. Associated with process and exploitation food breath tests square measure engaging as a result of these square measure safe, and supply a chance for quick purpose of care deciding the matter with a personality's health and gear for drug effectiveness method of deciding the price, amount, or quality of one thing throughout scientific investigative experiments. Our cluster has developed a rabbit enzyme breath check model to figure out the price, amount, or quality of the sensitivity and therefore the level of detail of enzyme primarily based detection of true bacteria dangerous respiratory organ sickness.

Commentary Pages: 1 - 2

The Natural History of Diabetic Kidney Disease and Treatment of Hyperglycemia in Patients with Type 2 Diabetes

Nsunaik Marik

DOI: 10.37421/cmcr.2021.5.170

Person with blood sugar disease I.e. Diabetes Mellitus (DM) organ that creates urine disease develops in about 40% of patients who are DM and is the leading cause of CKD worldwide. Although ESRD may be the most able to be known because of previous knowledge result of DM organ that creates urine disease, most patients actually die from disease of the heart and blood vessels and infections before needing organ that creates urine replacement therapy. The natural history of person with blood sugar disease, DM organ that creates urine disease includes glomerular hyperfiltration, progressive milk proteinuria, lowering in number GFR, and in the end, ESRD. Related to processing and using food changes connected with disease where blood sugar swings wildly leading to glomerular too much growth, glomerulosclerosis, and tubule interstitial swelling and fibrosis. Even though there is the existence of current therapies, there is large leftover risk of person with blood sugar disease, DM, organ that creates urine disease beginning and development or increase over time. Therefore, existing all over a large area invention of new things is very much needed to improve health results for patients with person with blood sugar disease organ that creates urine disease.

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