Journal of Lung Diseases & Treatment

ISSN: 2472-1018

Open Access

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Ramesh K

Cystic fibrosis is a life threatening disease resulted by a genetic mutation of the cystic fibrosis conductance regulator (CFTR) gene. CFTR gene encodes for a chloride channel, essential for the normal flow of salt and water movements across the cell membranes. There is an improper regulation which results in thickened secretions in lung, liver, reproductive organs and pancreas. Most men with cystic fibrosis (CF) are sterile due to failure of the seminal vesicle, vas deferens, body and tail of the epididymis to develop and ejaculatory duct. Particularly salty-tasting skin, persistent coughing, shortness of breath, frequent chest and lung infections and poor growth or weight gain are some of the symptoms of cystic fibrosis within the first year of a baby’s life [1]. Diabetes mellitus, episodic and chronic distal intestinal obstruction syndrome, osteoporosis, chronic liver disease, oesophageal reflux and oesophagitis, nasal polyposis, portal hypertension, allergic bronchopulmonary aspergillosis (ABPA), gallstones, respiratory and cardiac fai


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