Journal of Clinical Case Reports

Primary Squamous Cell Carcinoma of the Ureter in a Patient with No Risk Factors

Abstract

Yasser Alshomrani, Anmar Nassera and Abdulaziz Baazeem

Upper urinary tract squamous cell carcinomas are uncommon tumors. Several risk factors have been identified with this entity. We present a case primary squamous cell carcinoma of the distal ureter in an individual with no identifiable risk factors. The patient is a 70 year-old man who presented with bilateral flank pain. Laboratory investigations showed high serum creatinine. There was left hydronephrosis on ultrasonography. Computed Tomography (CT) showed an ill-defined soft tissue mass in the left ureter. A left retrograde pyelogram revealed a mass 4 cm from the ureterovesical junction, with ureter dilation proximal to it. The patient underwent distal ureterectomy and stented ureteroneocystostomy. Pathological study of the tumor revealed a moderately differentiated stage 3 invasive squamous cell carcinoma. On serial follow up, the patient showed significant improvement of the left hydronephrosis and improvement of the renal function. Two-year follow-up was negative for recurrence.