Polycystic liver disease (PLD) can be autosomal dominant or isolated with no renal impairment. The natural course of liver cysts is for them to grow in size and number, resulting in progressive disease that can lead to extremely large and incapacitating hepatomegaly. Only symptomatic hepatomegaly (pain, inability to eat, weight loss, dyspnea) or cystic complications like infection or intracranial haemorrhage should be treated. PLD treatment thus encompasses a wide range of therapeutic options, from non-intervention to liver transplantation, including needle aspiration evacuation with sclerosant injection, laparoscopic fenestration, and fenestration by laparotomy combined with liver resection. The choice of treatment is determined by the symptomatology, intrahepatic extension of the lesions, and the patient's overall health.
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Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report
