Journal of Nanosciences: Current Research

Pharmacological Properties of Cissus quadrangularis Loaded Silver Nanoparticles: An In-vitro Study

Abstract

Mounica Gummapu and Pavithra Amritkumar

Plant extracts traditionally used in ancient medical systems such as Ayurveda and Unani for thousands of years is now being revisited with interests turning towards utilizing them as biologically synthesized nanoparticles with better delivery. Cissus quadrangularis Linn. is one such important medicinal plant belonging to the family Vitaceae. In India, C. quadrangularis stems are widely used as medicine as well as in traditional cuisine owing to the presence of several bioactive compounds in it. In the present study, parts of C. quadrangularis plant were collected and ethanolic (Soxhlet and cold centrifuge) extracts were made from fresh and dried samples. Green synthesis of silver nanoparticles with extracted C. quadrangularis was carried out and its efficacy was checked. Phytochemical properties of C. quadrangularis extract was evaluated and various pharmacological properties such as anti-microbial, anti-oxidant, anti-inflammatory and anti-cancerous properties of both C. quadrangularis extracts and C. quadrangularis loaded sliver nanoparticles were assessed and compared. Overall, the green synthesized C. quadrangularis loaded silver nanoparticles had positive pharmacological properties, which were demonstrated in-vitro through this study.