Because of its osteogenic properties and biocompatibility, nano-hydroxyapatite is becoming more popular in dentistry. The current study's goal is to review the clinical applications of nano-HAp in dentistry. PubMeD and Scopus were used to conduct a literature search. A total of 154 articles were found. Following a review of the titles and abstracts, 122 articles were eliminated. Full-text analysis ruled out another six articles. The systematic review included 26 articles. Nano-HAp was used in three studies for tissue remineralization, eight studies for the treatment of dentin hypersensitivity, two studies for orthodontics, nine studies for graft material, and four studies for periodontology and implantology.
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