Microplastic pollution has become a global concern, posing significant threats to both the environment and human health. This study delved into the deleterious effects of microplastics and mercury on the European seabass (Dicentrarchus labrax), a marine fish widely consumed by humans. To investigate this, a short-term (96-hour) laboratory bioassay was conducted, wherein juvenile fish were subjected to varying concentrations of microplastics (0.26 and 0.69 mg/L), mercury (0.010 and 0.016 mg/L), and binary combinations of these substances at identical concentrations. These exposures were administered through test media. The outcomes of the study indicated that microplastics, mercury, and their combinations elicited toxic effects. Isolated exposure to microplastics and mercury led to neurotoxicity, as evidenced by the inhibition of Acetylcholinesterase (AChE) activity. Additionally, there was an observed increase in Lipid Oxidation (LPO) in both brain and muscle tissues, along with altered activities of energy-related enzymes, such as Lactate Dehydrogenase (LDH) and Isocitrate Dehydrogenase (IDH).
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Journal of Forensic Medicine received 165 citations as per Google Scholar report
